INT275802

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Context Info
Confidence 0.20
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.95
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Rem1) endoplasmic reticulum (Hcrt) GTPase activity (Rem1)
cellular_component (Rem1) biological_process (Rem1) cytoplasm (Hcrt)
Anatomy Link Frequency
neurons 1
Hcrt (Mus musculus)
Rem1 (Mus musculus)
Pain Link Frequency Relevance Heat
medulla 2 94.20 High High
Neuropeptide 4 89.60 High High
Locus ceruleus 20 78.88 Quite High
gABA 32 25.00 Low Low
amygdala 8 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Raphe 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 30 97.60 Very High Very High Very High
Sleep Disorders 80 96.76 Very High Very High Very High
Sprains And Strains 30 25.00 Low Low
Disease 2 19.52 Low Low
Overdose 8 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Vibrio Infection 4 5.00 Very Low Very Low Very Low
Sarcoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is not known how HCRT regulates REM sleep.
HCRT Regulation (regulates) of REM
1) Confidence 0.20 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2709920 Disease Relevance 0.44 Pain Relevance 0.08
It is still not known how HCRT regulates REM sleep or muscle tone since HCRT neurons are localized only in the lateral hypothalamus while REM sleep and muscle atonia are generated from the brainstem.
HCRT Regulation (regulates) of REM in neurons associated with medulla
2) Confidence 0.20 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2709920 Disease Relevance 0.51 Pain Relevance 0.09

General Comments

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