INT275807

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.38
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Sult2a2) cellular_component (Sult2a2) biological_process (Sult2a2)
Anatomy Link Frequency
spinal 1
neurons 1
Sult2a2 (Mus musculus)
Pain Link Frequency Relevance Heat
Acupuncture 21 87.20 High High
Pain 25 74.72 Quite High
Pain threshold 7 71.80 Quite High
nMDA receptor 3 70.40 Quite High
Paresthesia 1 69.80 Quite High
addiction 4 55.12 Quite High
Spinal cord 1 51.12 Quite High
Hippocampus 2 49.72 Quite Low
cerebral cortex 1 49.20 Quite Low
ischemia 1 37.20 Quite Low
Disease Link Frequency Relevance Heat
Pain 32 74.72 Quite High
Dysesthesia 1 69.80 Quite High
Drug Dependence 2 55.12 Quite High
Nociception 2 54.36 Quite High
Cognitive Disorder 3 53.16 Quite High
Cv General 4 Under Development 1 37.92 Quite Low
Epilepsy 1 36.40 Quite Low
Stress 1 35.60 Quite Low
Neurodegenerative Disease 1 15.56 Low Low
Anxiety Disorder 3 14.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the PREG synthase cytochrome P450 side-chain cleavage enzyme and hydroxysteroid sulfotransferase, which converts PREG to PREGS, are expressed in the brain [2], and these enzymes have been shown to colocalize in hippocampal neurons [38], suggesting local synthesis of PREGS.
Gene_expression (expressed) of hydroxysteroid sulfotransferase in neurons
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2710005 Disease Relevance 0.16 Pain Relevance 0.09
Acupoints ST36 and ST38 were selected because they are distant from the hand with minimal 'spinal segmental effects'.
Gene_expression (selected) of ST36 in spinal
2) Confidence 0.00 Published 2010 Journal Chin Med Section Body Doc Link PMC2942886 Disease Relevance 0.22 Pain Relevance 0.27

General Comments

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