INT276068

Context Info Confidence 0.02 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

nucleus (Ppp1cc, Myoz1) mitochondrion (Ppp1cc) carbohydrate metabolic process (Ppp1cc) protein complex (Ppp1cc) cytoplasm (Ppp1cc) chromosome (Ppp1cc)

Ppp1cc (Mus musculus) Myoz1 (Mus musculus)

Pain Link Frequency Relevance Heat Central nervous system 2 42.00 long-term potentiation 4 17.68 gABA 11 5.00 depression 9 5.00 imagery 5 5.00 interneuron 1 5.00 Kinase C 1 5.00 Dopamine 1 5.00 Serotonin 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Depression 9 5.00 Adhesions 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The limited influence of calcineurin activity on the Ca2+ threshold for RP induction is presumably attributable to its shorter-lasting effect on PP-1 activity and the lower affinity for Ca2+/CaM compared with PDE1.

PP-1 Binding (affinity) of calcineurin

1) Confidence 0.02 Published 2009 Journal Mol Syst Biol Section Body Doc Link PMC2710870 Disease Relevance 0 Pain Relevance 0

General Comments

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