INT276149

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Context Info
Confidence 0.78
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.56
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (SCG5) transport (SCG5) extracellular region (SCG5)
Anatomy Link Frequency
pituitary 3
SCG5 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 19 89.24 High High
Neuropeptide 4 57.28 Quite High
Neurotransmitter 4 55.84 Quite High
noradrenaline 1 50.08 Quite High
gABA 3 45.68 Quite Low
opiate 1 44.32 Quite Low
agonist 17 5.00 Very Low Very Low Very Low
Somatostatin 12 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Prolactinoma 3 96.72 Very High Very High Very High
Targeted Disruption 17 92.72 High High
Acromegaly 7 87.00 High High
Thyroid Disease 14 84.04 Quite High
Hyperphagia 1 45.52 Quite Low
Adenoma 14 33.12 Quite Low
Congenital Anomalies 4 32.20 Quite Low
Appetite Loss 13 30.80 Quite Low
Ganglion Cysts 1 7.00 Low Low
Hypogonadotropic Hypogonadism 3 6.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pituitary-hormone secretion by thyrotropinomas

Hormone secretion by somatotropinomas, corticotropinomas and prolactinomas exhibits increased pulse frequency, basal and pulsatile secretion, accompanied by greater disorderliness.

Localization (secretion) of Pituitary in Pituitary associated with prolactinoma
1) Confidence 0.78 Published 2008 Journal Pituitary Section Title Doc Link PMC2712623 Disease Relevance 0.32 Pain Relevance 0
Whereas obestatin (probably better termed, ghrelin-associated peptide) does not alter pituitary hormone secretion [402], this peptide may suppress thirst, promote beta-cell survival and regeneration, activate urocortin-2 pathways and thereby inhibit gastroduodenal peristalsis, and induce early-response genes in gastric mucosa and preadipocytes [403–410].
Localization (secretion) of pituitary in pituitary
2) Confidence 0.78 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2925380 Disease Relevance 0.24 Pain Relevance 0.04
At puberty the pulsatile GnRH secretion, and the subsequent episodic pituitary gonadotropin secretion, which is necessary for normal gonadal development and function, is triggered by the activation of the GnRH pulse generator.
Localization (secretion) of pituitary in pituitary
3) Confidence 0.78 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2958977 Disease Relevance 0 Pain Relevance 0.08

General Comments

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