INT276174

Context Info Confidence 0.34 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.63 Pain Relevance 0.47

mitochondrion (Pten) aging (Pten) plasma membrane (Pten) nucleus (Pten) intracellular (Pten) enzyme binding (Pten)

Pten (Rattus norvegicus)

Pain Link Frequency Relevance Heat Paracetamol 60 92.68 cytokine 1 5.00

Disease Link Frequency Relevance Heat Aging 38 96.48 Hyperglycemia 4 93.68 Obesity 2 77.48 Apoptosis 10 12.64 Frailty 5 11.52 Body Weight 4 5.00 Death 2 5.00 Hypoxia 1 5.00 Insulin Resistance 1 5.00 Hypertrophy 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It is thought that high glucose levels can result in decreased PTEN expression and decreases in PTEN phosphatase activity [14].

Regulation (result) of Negative_regulation (decreases) of PTEN

1) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2712760 Disease Relevance 0.63 Pain Relevance 0.47

General Comments

This test has worked.