INT276202

Context Info Confidence 0.32 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.78 Pain Relevance 0.42

mitochondrion (Pten) aging (Pten) plasma membrane (Pten) nucleus (Pten) intracellular (Pten) enzyme binding (Pten)

Anatomy Link Frequency tail 2 Pten (Rattus norvegicus)

Pain Link Frequency Relevance Heat Paracetamol 60 94.80 cytokine 1 5.00

Disease Link Frequency Relevance Heat Aging 38 92.64 Hyperglycemia 4 89.84 Obesity 2 61.36 Apoptosis 10 43.60 Frailty 5 42.48 Body Weight 4 5.00 Death 2 5.00 Hypoxia 1 5.00 Insulin Resistance 1 5.00 Hypertrophy 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It has also been documented that phosphorylation of the C-terminal tail of PTEN decreases the degradation of PTEN protein by increasing its stability [29].

Negative_regulation (decreases) of Protein_catabolism (degradation) of PTEN protein in tail

1) Confidence 0.32 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2712760 Disease Relevance 0.78 Pain Relevance 0.42

General Comments

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