INT276218

Context Info Confidence 0.26 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0.46

aging (Akt1, Pten) enzyme binding (Akt1, Pten) cytoplasm (Akt1, Pten) nucleus (Akt1, Pten) plasma membrane (Akt1, Pten) nucleoplasm (Akt1)

Akt1 (Rattus norvegicus) Pten (Rattus norvegicus)

Pain Link Frequency Relevance Heat Paracetamol 60 98.12 cytokine 1 5.00

Disease Link Frequency Relevance Heat Aging 38 76.32 Apoptosis 10 5.00 Frailty 5 5.00 Body Weight 4 5.00 Hyperglycemia 4 5.00 Death 2 5.00 Obesity 2 5.00 Hypoxia 1 5.00 Insulin Resistance 1 5.00 Hypertrophy 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Akt hyper-phosphorylation is associated with a loss of PTEN protein

Akt Binding (associated) of PTEN protein

1) Confidence 0.26 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2712760 Disease Relevance 0.08 Pain Relevance 0.46

General Comments

This test has worked.