INT276228

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.18
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PPARG) enzyme binding (PPARG) DNA binding (PPARG)
lipid metabolic process (PPARG) cytoplasm (PPARG) cytosol (PPARG)
Anatomy Link Frequency
skin 1
Nrtim1 (Mus musculus)
PPARG (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 78 99.90 Very High Very High Very High
agonist 7 24.96 Low Low
Inflammation 5 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
cOX1 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 23 99.60 Very High Very High Very High
Nevus 15 99.48 Very High Very High Very High
Skin Cancer 59 99.38 Very High Very High Very High
Cancer 46 91.92 High High
Disease 6 89.00 High High
Recurrence 3 47.44 Quite Low
Malignant Neoplastic Disease 5 39.68 Quite Low
Melanoma 12 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Reprotox - General 1 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with previously published data on melanocytic skin lesions [6, 7] our immunohistochemical analysis of benign nevi, primary MM and MM metastases show that COX2 and PPARG immunoreactivity significantly increases from benign nevi to primary MM and MM metastases.
immunoreactivity Positive_regulation (increases) of PPARG in skin associated with nevus, cox2, skin cancer and metastasis
1) Confidence 0.01 Published 2010 Journal PPAR Research Section Body Doc Link PMC2712952 Disease Relevance 2.18 Pain Relevance 0.14

General Comments

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