INT276372

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Context Info
Confidence 0.38
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.49
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

growth (FOXP3) nucleus (FOXP3) intracellular (FOXP3)
embryo development (FOXP3) protein complex (FOXP3) cytoplasm (FOXP3)
Anatomy Link Frequency
skin 2
FOXP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 38 98.22 Very High Very High Very High
antagonist 1 74.16 Quite High
Inflammation 33 57.20 Quite High
Multiple sclerosis 1 10.20 Low Low
Crohn's disease 4 9.24 Low Low
psoriasis 1 8.56 Low Low
rheumatoid arthritis 2 8.12 Low Low
tolerance 13 5.00 Very Low Very Low Very Low
chemokine 8 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphomatoid Papulosis 4 98.24 Very High Very High Very High
Lymphatic System Cancer 122 90.08 High High
Anaplastic Large Cell Lymphoma 20 89.12 High High
Cancer 74 73.36 Quite High
Syndrome 7 72.16 Quite High
Malignant Neoplastic Disease 8 58.80 Quite High
INFLAMMATION 31 57.20 Quite High
Hodgkin's Disease 25 32.32 Quite Low
Epstein-barr Virus 30 20.96 Low Low
Communicable Diseases 3 19.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rather in the presence of proinflammatory cytokines and low concentration of TGF-beta, RORgammat expression is further upregulated, whereas FoxP3 expression and function are inhibited.
Negative_regulation (inhibited) of Gene_expression (expression) of FoxP3 associated with cytokine
1) Confidence 0.38 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2821644 Disease Relevance 0.06 Pain Relevance 0.13
Gjeerdrum et al. studied the expression of FoxP3 as a marker of Tregs in skin biopsies from lymphomatoid papulosis (LyP) (n?
Negative_regulation (studied) of Gene_expression (expression) of FoxP3 in skin associated with lymphomatoid papulosis
2) Confidence 0.10 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 1.44 Pain Relevance 0.04

General Comments

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