INT276403

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.37
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MALT1) peptidase activity (MALT1) nucleolus (MALT1)
nucleus (MALT1) protein complex (MALT1) cytoplasm (MALT1)
MALT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 12 66.16 Quite High
Central nervous system 26 23.28 Low Low
headache 4 14.84 Low Low
nud 16 5.00 Very Low Very Low Very Low
cINOD 10 5.00 Very Low Very Low Very Low
peptic ulcer disease 6 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 12 100.00 Very High Very High Very High
Chromosome Aberrations 4 99.98 Very High Very High Very High
Epstein-barr Virus 10 96.68 Very High Very High Very High
Cancer 37 93.00 High High
Lymphatic System Cancer 103 92.40 High High
Disease 29 88.28 High High
Generaliased Trisomy 4 88.08 High High
Gastroesophageal Reflux Disease 15 80.48 Quite High
Disease Progression 1 76.12 Quite High
Residual Neoplasm 1 73.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Streubel et al. [24] have identified a second chromosomal aberration involving the MALT1 gene and IgH on 14q32 rather than the API2.
Regulation (involving) of MALT1 gene associated with chromosome aberrations
1) Confidence 0.34 Published 2008 Journal J Hematop Section Body Doc Link PMC2713483 Disease Relevance 1.33 Pain Relevance 0.03
The FISH study for MALT1 translocations showed a rearrangement of the MALT1 region at 18q21 in 30% of the interphase cells.
Regulation (rearrangement) of MALT1
2) Confidence 0.34 Published 2008 Journal J Hematop Section Body Doc Link PMC2713483 Disease Relevance 0.88 Pain Relevance 0
This translocation is associated with API2-MALT1 fusion, the former being involved in regulation of apoptosis and the latter resembling a caspase-like protein, with an as yet unknown biological function.
Regulation (regulation) of caspase-like protein associated with apoptosis
3) Confidence 0.01 Published 2007 Journal J Gastroenterol Section Body Doc Link PMC2780612 Disease Relevance 1.16 Pain Relevance 0

General Comments

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