INT276409

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Context Info
Confidence 0.54
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 11
Disease Relevance 0.73
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ctbp2) oxidoreductase activity (Ctbp2) nucleus (Ctbp2)
Anatomy Link Frequency
pinealocytes 3
Ctbp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 30 5.00 Very Low Very Low Very Low
Neurotransmitter 20 5.00 Very Low Very Low Very Low
anesthesia 12 5.00 Very Low Very Low Very Low
noradrenaline 10 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 23 95.96 Very High Very High Very High
Retinal Diseases 8 91.44 High High
Muscular Dystrophy 11 74.72 Quite High
Disease 8 72.16 Quite High
Muscle Disease 1 66.72 Quite High
Ganglion Cysts 2 51.08 Quite High
Respiratory Syncytial Virus 13 37.48 Quite Low
Decapitation 10 5.00 Very Low Very Low Very Low
Body Weight 10 5.00 Very Low Very Low Very Low
Sunburn 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The colocalization of eGFP and CtBP2 strongly suggest that the OPL layer was transduced (Figure 2F,H).
Localization (colocalization) of CtBP2
1) Confidence 0.54 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2713732 Disease Relevance 0.73 Pain Relevance 0
Proteins that completely co-localized with RIBEYE included CtBP1 (Fig. 3c,d), Bassoon (Fig. 4b), and Piccolo (Fig. 4d).
Localization (localized) of RIBEYE
2) Confidence 0.42 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
m (e–h)Fig. 3Association of SRs with RIBEYE and CtBP1 in rat pinealocytes under light and dark conditions. a, b As seen in the merged image (merge) of the high power confocal laser-scanning images, RIBEYE-B-labeled (RIB B) SRs (red) completely co-localize (examples marked by arrowheads) with RIBEYE A (RIB A; green), irrespective of day (a) or night (b) conditions.
Localization (localize) of RIBEYE in pinealocytes
3) Confidence 0.39 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
To investigate whether RIBEYE was specifically localized at pinealocyte SRs, postembedding immunogold electron microscopy was performed with antibodies against the A- and B-domains of RIBEYE.
Localization (localized) of RIBEYE in pinealocyte
4) Confidence 0.37 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
Note that Bassoon (b) and Piccolo (d) are completely co-localized with RIBEYE in contrast to KIF3A, which is only partially co-localized with RIBEYE.
Localization (localized) of RIBEYE
5) Confidence 0.34 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
By contrast, the staining for Bassoon, Piccolo, and Munc13–1 and their colocalization with RIBEYE was weak during the day and strong at night (Fig. 4a–f).
Localization (colocalization) of RIBEYE
6) Confidence 0.34 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
CtBP1 co-localized with RIBEYE to a similar extent during the day and night (Fig. 3c,d).
Localization (localized) of RIBEYE
7) Confidence 0.34 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
To this end, RIBEYE and the CAZ proteins under consideration were studied by immunocytochemical co-localization.
Localization (localization) of RIBEYE
8) Confidence 0.34 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
Note that Bassoon (b) and Piccolo (d) are completely co-localized with RIBEYE in contrast to KIF3A, which is only partially co-localized with RIBEYE.
Localization (localized) of RIBEYE
9) Confidence 0.34 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
m (e–h)Fig. 3Association of SRs with RIBEYE and CtBP1 in rat pinealocytes under light and dark conditions. a, b As seen in the merged image (merge) of the high power confocal laser-scanning images, RIBEYE-B-labeled (RIB B) SRs (red) completely co-localize (examples marked by arrowheads) with RIBEYE A (RIB A; green), irrespective of day (a) or night (b) conditions.
Localization (localize) of RIBEYE-B-labeled in pinealocytes
10) Confidence 0.34 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
Munc13–1 and the scaffolding proteins Bassoon and Piccolo co-localize with RIBEYE to a greater extent at night.
Localization (localize) of RIBEYE
11) Confidence 0.32 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0

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