INT276424

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Context Info
Confidence 0.32
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.60
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (IMPACT) cellular_component (IMPACT) biological_process (IMPACT)
IMPACT (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 147 99.84 Very High Very High Very High
Duloxetine 84 98.92 Very High Very High Very High
Pain 57 92.16 High High
Pain score 16 69.68 Quite High
tolerance 3 18.80 Low Low
pregabalin 63 5.00 Very Low Very Low Very Low
depression 20 5.00 Very Low Very Low Very Low
sNRI 12 5.00 Very Low Very Low Very Low
cva 11 5.00 Very Low Very Low Very Low
tricyclic antidepressant 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibromyalgia 147 99.84 Very High Very High Very High
Infection 76 96.64 Very High Very High Very High
Reprotox - General 3 40 95.44 Very High Very High Very High
Dengue 122 95.40 Very High Very High Very High
Premature Birth 137 94.80 High High
Disease 67 92.32 High High
Pain 83 92.16 High High
Depression 36 89.16 High High
Togavirus Infection 1 88.52 High High
Hepatitis B Virus Infection 1 80.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In populations where high infant mortality rates and high stillbirth rates are common, a degree of fatalism may impact the experience and reporting of fetal or neonatal loss.
Negative_regulation (loss) of impact
1) Confidence 0.32 Published 2010 Journal BMC Pregnancy Childbirth Section Body Doc Link PMC2841776 Disease Relevance 0.86 Pain Relevance 0
Beyond its impact on drug costs, there was little short term data regarding the economic impact of growth hormone on other healthcare resources, and complete absence of long-term data, all of which severely limited interpretation and assessment of component E3 (Impact on other spending).


Negative_regulation (limited) of Impact on other spending
2) Confidence 0.14 Published 2010 Journal Cost Eff Resour Alloc Section Body Doc Link PMC2856527 Disease Relevance 0 Pain Relevance 0
Duloxetine-treated patients experienced a significantly greater reduction in the total impact of FM symptoms and improvement in mood, quality of life, and function than patients who received placebo.
Negative_regulation (reduction) of impact associated with fibrositis and duloxetine
3) Confidence 0.14 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004640 Disease Relevance 0.64 Pain Relevance 0.72
Pathogen reduction technology is not yet available for red cells, and this has somewhat limited its impact.
Negative_regulation (limited) of impact
4) Confidence 0.03 Published 2009 Journal Transfusion Medicine (Oxford, England) Section Body Doc Link PMC2713854 Disease Relevance 1.09 Pain Relevance 0

General Comments

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