INT276438

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Context Info
Confidence 0.12
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.21
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (OPN1SW) plasma membrane (OPN1SW) signal transducer activity (OPN1SW)
OPN1SW (Homo sapiens)
MYP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
sSRI 3 100.00 Very High Very High Very High
antidepressant 3 77.04 Quite High
depression 8 5.00 Very Low Very Low Very Low
Paresthesia 6 5.00 Very Low Very Low Very Low
Migraine 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eating Disorder 76 100.00 Very High Very High Very High
Depression 11 100.00 Very High Very High Very High
Weight Loss 15 98.00 Very High Very High Very High
Obesity 32 70.12 Quite High
Epilepsy 3 65.28 Quite High
Appetite Loss 7 61.56 Quite High
Overweight 1 57.64 Quite High
Kidney Stones 1 54.64 Quite High
Hypospadias 1 25.84 Quite Low
Dysesthesia 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Topiramate appears to have a weight loss effect greater than those of other effective and well studied treatments for this disorder such as CBT, interpersonal therapy, and SSRIs, and one comparable to that of sibutramine.13 As noted above, depressive symptoms are frequently associated with BED, but as yet no compelling evidence exists of the efficacy of topiramate on this symptom dimension.
CBT Binding (associated) of BED associated with depression, weight loss, ssri and eating disorder
1) Confidence 0.12 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2714287 Disease Relevance 1.21 Pain Relevance 0.09

General Comments

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