INT276511

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nts)
Nts (Rattus norvegicus)
Mir431 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 46 97.20 Very High Very High Very High
Spinal cord 18 55.44 Quite High
Dorsal horn 11 51.12 Quite High
Pain 47 50.00 Quite Low
intrathecal 9 43.04 Quite Low
Inflammation 14 16.80 Low Low
Analgesic 13 5.00 Very Low Very Low Very Low
Lasting pain 11 5.00 Very Low Very Low Very Low
Antinociceptive 10 5.00 Very Low Very Low Very Low
analgesia 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 61 50.00 Quite Low
Nociception 45 35.68 Quite Low
INFLAMMATION 15 16.80 Low Low
Ganglion Cysts 5 5.00 Very Low Very Low Very Low
Inflammatory Pain 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 3 5.00 Very Low Very Low Very Low
Low Back Pain 2 5.00 Very Low Very Low Very Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

2 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, the metabolically stable NT(8–13) analog JMV-431, protected at its N-terminus by a Boc group and by a reduced pseudopeptide bond Y(CH2NH) in position 11–12 binds with 250 times greater affinity to rat NTS2 (IC50 = 19 ± 3 nM) than to rat NTS1 (IC50 = 4735 ± 100 nM).
NTS2 Binding (binds) of JMV-431
1) Confidence 0.00 Published 2009 Journal Mol Pain Section Body Doc Link PMC2714839 Disease Relevance 0 Pain Relevance 0.10

General Comments

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