INT27652
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
On histological examination, the tall cell variant in the femur was producing abundant thyroglobulin. | |||||||||||||||
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It was not performed when serum thyroglobulin was detectable (? | |||||||||||||||
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Serum thyroglobulin levels were measured both while the patient was receiving levothyroxine and during TSH stimulation, which was achieved by abstaining from levothyroxine administration or by administering recombinant human TSH (rhTSH) for patients judged to tolerate abstaining from levothyroxine poorly (n? | |||||||||||||||
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Thyroglobulin levels at the first and last 13-CRA RDT application are depicted in additional file 1: thyroglobulin before and after 13-CRA RDT. | |||||||||||||||
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A double histochemical approach (Alcian blue-periodic acid-Schiff and Alcian blue-high-iron diamine) combined with ultrastructural investigation confirmed the presence of true mucus, ruling out the presence of breakdown products of thyroglobulin. | |||||||||||||||
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Radioiodine ablation was repeated whenever serum thyroglobulin was detectable or when abnormal uptake was present in the thyroid bed or at extrathyroid sites in a diagnostic radioiodine scan. | |||||||||||||||
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Last step was to determine if there was expression of cell-specific structures or receptors that are unique identifiers of cell types, for example neuroendocrine granules, peptide hormones, thyroglobulin, Prostate Specific Antigen (PSA), Gross Cystic Disease Fluid Protein (GCDFP) or Thyroid Transcription Factor-1 (TTF-1). | |||||||||||||||
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The groups with and without TSAb were comparable with regard to sex, age, anti-inflammatory drugs, serum thyroglobulin levels, antithyroglobulin and antimicrosomal antibodies, rheumatoid factor, as well as to the serum levels of thyroxine and 3, 5, 3'-triiodothyronine. | |||||||||||||||
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The use of RAI for all three purposes relies on the ability of both normal and malignant thyroid tissue to transport iodine for synthesis of thyroglobulin, triiodothyronine and thyroxine in response to TSH. | |||||||||||||||
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Tg-on had become detectable in 1 of 14 patients, Tg and TSH levels did not significantly differ (p? | |||||||||||||||
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Tg-on was lower but remained detectable in both patients (table 3). | |||||||||||||||
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Tg-on after radiodine treatment remained detectable in one of both patients (2.6 ng/ml). | |||||||||||||||
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Furthermore, immunoperoxidase stains for thyroglobulin and TTF-1 were negative, excluding the possibility of a thyroid neoplasm. | |||||||||||||||
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Seventeen (95%) of 19 patients for whom serial thyroglobulin levels were available showed a marked and rapid response in thyroglobulin levels with a mean decrease of 70%. | |||||||||||||||
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Seventeen (95%) of 19 patients for whom serial thyroglobulin levels were available showed a marked and rapid response in thyroglobulin levels with a mean decrease of 70%. | |||||||||||||||
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-enkephalin, neuron-specific enolase, chromogranin and neurofilaments, and negative for thyroglobulin and S-100 protein. | |||||||||||||||
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Tg-on was undetectable in 115 patients. | |||||||||||||||
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Group 3: Patients with undetectable Tg-on (<0.6 ng/ml) | |||||||||||||||
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For it is known that lymph node metastases can be detected by neck ultrasound in patients with both undetectable Tg-on and undetectable rhTSH stimulated Tg or Tg-off [16], [17]. | |||||||||||||||
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Actually, this result only confirmed the already known absence of disease in these patients with undetectable Tg-on. | |||||||||||||||
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General Comments
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