INT276537

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Context Info
Confidence 0.65
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.16
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Myh10) plasma membrane (Myh10) cytoplasm (Myh10)
Anatomy Link Frequency
diaphragm 1
podocyte 1
Myh10 (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 4 5.00 Very Low Very Low Very Low
member 8 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 22 88.88 High High
Nephrotic Syndrome 16 5.00 Very Low Very Low Very Low
Renal Disease 12 5.00 Very Low Very Low Very Low
Stress 8 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Renal Failure 6 5.00 Very Low Very Low Very Low
Chronic Renal Failure 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since 7 of these proteins (as well as Myh10) have been shown to be localized to podocyte foot processes, these collective observations raise an interesting speculation that a number of the RNA transcripts we identified may similarly be localized at the slit diaphragm.
Localization (localized) of Myh10 in diaphragm
1) Confidence 0.65 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714980 Disease Relevance 0 Pain Relevance 0
Eight of encoded proteins have been directly shown to localize to the podocyte foot processes, including the slit diaphragm: myosin IIa (Myh9), myosin IIb (Myh10), drebrin (Dbn1), spectrin-?
Localization (localize) of myosin IIb in podocyte
2) Confidence 0.53 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714980 Disease Relevance 0.16 Pain Relevance 0

General Comments

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