INT276574

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 0.50
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
podocyte 2
KTWS (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 14 91.96 High High
member 8 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 77 84.52 Quite High
Renal Failure 21 77.04 Quite High
Frasier Syndrome 14 68.56 Quite High
Stress 28 47.76 Quite Low
Congenital Anomalies 7 39.60 Quite Low
Renal Disease 42 31.52 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 7 30.60 Quite Low
Cancer 21 26.24 Quite Low
Nephrotic Syndrome 56 22.00 Low Low
Denys-drash Syndrome 7 19.40 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In order to investigate the role of the TEV protease, three separate pulldowns were completed using cell extracts from MPC-5 cells stably expressing WT1(+KTS).
Gene_expression (expressing) of KTS
1) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714980 Disease Relevance 0 Pain Relevance 0
For this validation two independent pulldowns were performed using fully differentiated WT1(+KTS) expressing MPC-5 cells.
Gene_expression (expressing) of KTS
2) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714980 Disease Relevance 0 Pain Relevance 0
Additional pulldowns were performed, using cell extracts from MPC-5 cells stably expressing WT1(+KTS)-FF-ZZ, but also using control cell extracts from MPC-5 cells expressing the empty vector plasmid.
Gene_expression (expressing) of KTS
3) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714980 Disease Relevance 0.06 Pain Relevance 0
In order to identify potential candidate mRNAs associating with WT1(+KTS), WT1(+KTS) was purified from cell extracts from a podocyte cell line stably expressing an epitope tagged WT1(+KTS) construct.
Gene_expression (expressing) of KTS in podocyte
4) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714980 Disease Relevance 0.15 Pain Relevance 0
In order to identify potential candidate mRNAs associating with WT1(+KTS), WT1(+KTS) was purified from cell extracts from a podocyte cell line stably expressing an epitope tagged WT1(+KTS) construct.
Gene_expression (expressing) of KTS in podocyte
5) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714980 Disease Relevance 0.14 Pain Relevance 0
MPC-5 cells were established with stable expression of the WT1(+KTS) cDNA containing the FF-ZZ tag.
Gene_expression (expression) of KTS
6) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714980 Disease Relevance 0.08 Pain Relevance 0.03
Cell extracts were prepared from WT1(+KTS)-FF-ZZ expressing MPC-5 cells that were allowed to differentiate at 37°C for 14 days.
Gene_expression (expressing) of KTS
7) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714980 Disease Relevance 0.08 Pain Relevance 0.05

General Comments

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