INT276619

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.57
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cdh1) cell adhesion (Cdh1) Golgi apparatus (Cdh1)
plasma membrane (Cdh1) cytoplasm (Cdh1)
Anatomy Link Frequency
small intestine 2
Cdh1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 20 99.00 Very High Very High Very High
cytokine 8 9.12 Low Low
cINOD 10 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
spastic colon 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 28 99.00 Very High Very High Very High
Inflammatory Bowel Disease 4 87.04 High High
Pressure And Volume Under Development 4 76.40 Quite High
Ulcers 2 59.12 Quite High
Congenital Anomalies 16 58.20 Quite High
Toxicity 2 44.80 Quite Low
Celiac Disease 26 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Weight Gain 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Administration of indomethacin to gluten-sensitized mice led to more pronounced barrier dysfunction, which was accompanied by a mild pro-inflammatory shift with marked changes in EC ultra-structure, reduced E-cadherin mRNA levels in the proximal small intestine and generation of systemic antibody responses to intestinal microbiota.
Negative_regulation (reduced) of Transcription (levels) of E-cadherin in small intestine associated with inflammation
1) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2715133 Disease Relevance 0.38 Pain Relevance 0.09
Concomitant treatment with indomethacin and gluten led to reduction of E-cadherin mRNA expression
Negative_regulation (reduction) of Transcription (expression) of E-cadherin
2) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2715133 Disease Relevance 0.19 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox