INT276671

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Context Info
Confidence 0.23
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 1.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prkcg) plasma membrane (Prkcg) nucleus (Prkcg)
intracellular (Prkcg) response to stress (Prkcg) cytoplasm (Prkcg)
Prkcg (Rattus norvegicus)
Nav1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nav1.8 65 100.00 Very High Very High Very High
Kinase C 38 100.00 Very High Very High Very High
substance P 66 94.40 High High
tetrodotoxin 17 86.88 High High
dorsal root ganglion 43 84.56 Quite High
Pain 11 66.88 Quite High
Peripheral sensitization 1 66.56 Quite High
calcitonin gene related peptide 1 58.12 Quite High
Neuropeptide 2 56.84 Quite High
hyperexcitability 1 39.12 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 45 84.56 Quite High
Pain 13 66.88 Quite High
Inflammatory Pain 3 22.76 Low Low
Neuropathic Pain 3 21.56 Low Low
Hyperalgesia 5 20.96 Low Low
INFLAMMATION 11 15.80 Low Low
Nociception 3 7.44 Low Low
Nervous System Injury 1 5.00 Very Low Very Low Very Low
Rupture 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There are many other papers confirmed the enhancement of Nav1.8 by PKC pathway [24,48,49].
PKC Positive_regulation (enhancement) of Nav1.8 associated with kinase c and nav1.8
1) Confidence 0.23 Published 2009 Journal Mol Pain Section Body Doc Link PMC2715383 Disease Relevance 0.21 Pain Relevance 1.55

General Comments

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