INT276687

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 1.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pax3, Nkx1-1) cell proliferation (Pax3) DNA binding (Pax3)
neurological system process (Nkx1-1)
Anatomy Link Frequency
primary sensory neurons 1
Pax3 (Mus musculus)
Nkx1-1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 66 100.00 Very High Very High Very High
dorsal root ganglion 43 100.00 Very High Very High Very High
Dorsal horn neuron 1 94.24 High High
Spinal cord 4 89.04 High High
Pain 11 86.88 High High
tetrodotoxin 17 75.12 Quite High
sodium channel 5 74.00 Quite High
nociceptor 2 70.24 Quite High
Action potential 7 65.84 Quite High
nav1.8 65 64.16 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 45 100.00 Very High Very High Very High
Pain 13 86.88 High High
Nociception 3 44.16 Quite Low
INFLAMMATION 11 39.20 Quite Low
Hyperalgesia 5 38.16 Quite Low
Neuropathic Pain 3 26.16 Quite Low
Inflammatory Pain 3 14.00 Low Low
Nervous System Injury 1 5.00 Very Low Very Low Very Low
Rupture 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A growing body of evidence showed that SP could activate DRG neurons through NK-1 receptor in primary sensory neurons [10-13,34,35], in despite of a contradictory report [36].
SP Positive_regulation (activate) of NK-1 in primary sensory neurons associated with dorsal root ganglion and substance p
1) Confidence 0.00 Published 2009 Journal Mol Pain Section Body Doc Link PMC2715383 Disease Relevance 0.59 Pain Relevance 1.47

General Comments

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