INT276836

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Context Info
Confidence 0.70
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.19
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gpr65) plasma membrane (Gpr65) signal transducer activity (Gpr65)
Anatomy Link Frequency
neurons 1
Gpr65 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 200 98.88 Very High Very High Very High
Thermal hyperalgesia 16 96.16 Very High Very High Very High
ASIC 8 94.20 High High
IPN 112 91.20 High High
imagery 12 70.88 Quite High
qutenza 176 11.60 Low Low
Hyperalgesia 92 5.00 Very Low Very Low Very Low
Pain 56 5.00 Very Low Very Low Very Low
withdrawal 40 5.00 Very Low Very Low Very Low
Kinase C 36 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 204 98.88 Very High Very High Very High
Hyperalgesia 108 96.16 Very High Very High Very High
Inflammatory Pain 112 91.20 High High
Bordatella Infection 8 35.60 Quite Low
Pressure And Volume Under Development 84 5.00 Very Low Very Low Very Low
Pain 64 5.00 Very Low Very Low Very Low
Nociception 36 5.00 Very Low Very Low Very Low
Hypersensitivity 24 5.00 Very Low Very Low Very Low
Acidosis 8 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Given that 40% of TRPV1-positive neurons express TDAG8 [28,29], we wondered whether co-localization of TRPV1 and TDAG8 is changed after CFA injection.
Localization (localization) of TDAG8 in neurons
1) Confidence 0.70 Published 2009 Journal Mol Pain Section Body Doc Link PMC2716309 Disease Relevance 0.42 Pain Relevance 0.35
Co-localization of TDAG8 with TRPV1 increased after inflammation
Localization (localization) of TDAG8 associated with inflammation
2) Confidence 0.70 Published 2009 Journal Mol Pain Section Body Doc Link PMC2716309 Disease Relevance 0.36 Pain Relevance 0.30
Co-localization of TDAG8 and TRPV1 was examined in pairs of continuous 6-?
Spec (examined) Localization (localization) of TDAG8
3) Confidence 0.70 Published 2009 Journal Mol Pain Section Body Doc Link PMC2716309 Disease Relevance 0.42 Pain Relevance 0.35
TDAG8 and TRPV1 were cloned into the vector pIRES-hrGFP-2a (pIRES-GFP) for transfection experiments.
Localization (cloned) of TDAG8
4) Confidence 0.57 Published 2009 Journal Mol Pain Section Body Doc Link PMC2716309 Disease Relevance 0 Pain Relevance 0.04

General Comments

This test has worked.

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