INT276843

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.85
Pain Relevance 3.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gpr65) plasma membrane (Gpr65) signal transducer activity (Gpr65)
Gpr65 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 36 99.64 Very High Very High Very High
qutenza 176 99.44 Very High Very High Very High
Inflammation 200 99.24 Very High Very High Very High
IPN 112 95.44 Very High Very High Very High
Hyperalgesia 92 94.00 High High
ASIC 8 76.84 Quite High
Thermal hyperalgesia 16 50.28 Quite High
nociceptor 28 49.40 Quite Low
Pain 56 5.00 Very Low Very Low Very Low
withdrawal 40 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 204 99.24 Very High Very High Very High
Inflammatory Pain 112 95.44 Very High Very High Very High
Hyperalgesia 108 94.00 High High
Nociception 36 51.92 Quite High
Pressure And Volume Under Development 84 5.00 Very Low Very Low Very Low
Pain 64 5.00 Very Low Very Low Very Low
Hypersensitivity 24 5.00 Very Low Very Low Very Low
Bordatella Infection 8 5.00 Very Low Very Low Very Low
Acidosis 8 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TDAG8 activation sensitizes TRPV1 response to capsaicin
Positive_regulation (sensitizes) of Positive_regulation (activation) of TDAG8 associated with qutenza
1) Confidence 0.44 Published 2009 Journal Mol Pain Section Body Doc Link PMC2716309 Disease Relevance 0.13 Pain Relevance 0.56
TDAG8 activation elevates cAMP levels, activating PKA and PKC?.
Positive_regulation (activating) of Positive_regulation (activation) of TDAG8 associated with kinase c
2) Confidence 0.44 Published 2009 Journal Mol Pain Section Body Doc Link PMC2716309 Disease Relevance 0.74 Pain Relevance 0.97
The enhanced response of TRPV1 to capsaicin was possibly due to proton-induced TDAG8 activation.
Positive_regulation (induced) of Positive_regulation (activation) of TDAG8 associated with qutenza
3) Confidence 0.41 Published 2009 Journal Mol Pain Section Body Doc Link PMC2716309 Disease Relevance 0.25 Pain Relevance 0.79
Accordingly, peripheral inflammation induces a local increase of protons, leading to TDAG8 activation.
Positive_regulation (leading) of Positive_regulation (activation) of TDAG8 associated with inflammation
4) Confidence 0.41 Published 2009 Journal Mol Pain Section Body Doc Link PMC2716309 Disease Relevance 0.73 Pain Relevance 0.97

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox