INT276865

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Context Info
Confidence 0.25
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Trpv1, Gpr65) cytosol (Trpv1) signal transduction (Gpr65)
transport (Trpv1) signal transducer activity (Gpr65) transmembrane transport (Trpv1)
Anatomy Link Frequency
neurons 3
Trpv1 (Mus musculus)
Gpr65 (Mus musculus)
Pain Link Frequency Relevance Heat
Thermal hyperalgesia 4 100.00 Very High Very High Very High
Inflammation 50 99.54 Very High Very High Very High
Hyperalgesia 23 99.08 Very High Very High Very High
nociceptor 7 90.16 High High
qutenza 44 67.68 Quite High
IPN 28 46.72 Quite Low
chemokine 1 19.40 Low Low
ASIC 2 19.20 Low Low
Pain 14 5.00 Very Low Very Low Very Low
withdrawal 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperalgesia 27 100.00 Very High Very High Very High
INFLAMMATION 51 99.54 Very High Very High Very High
Nociception 9 70.24 Quite High
Inflammatory Pain 28 46.72 Quite Low
Adhesions 1 36.08 Quite Low
Congenital Anomalies 1 30.48 Quite Low
Apoptosis 1 5.36 Low Low
Pressure And Volume Under Development 21 5.00 Very Low Very Low Very Low
Pain 16 5.00 Very Low Very Low Very Low
Hypersensitivity 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The plasticity of A-fiber neurons is an important mechanism that causes hyperalgesia following inflammation, therefore, increased TDAG8 expression in A-fiber could be involved in mechanical and thermal hyperalgesia by regulating TRPV1 function.
Regulation (regulating) of TRPV1 in neurons Regulation (involved) of Gene_expression (expression) of TDAG8 in neurons associated with hyperalgesia, inflammation and thermal hyperalgesia
1) Confidence 0.25 Published 2009 Journal Mol Pain Section Body Doc Link PMC2716309 Disease Relevance 0.62 Pain Relevance 0.76

General Comments

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