INT27687

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Context Info
Confidence 0.53
First Reported 1985
Last Reported 2011
Negated 4
Speculated 7
Reported most in Abstract
Documents 20
Total Number 27
Disease Relevance 9.75
Pain Relevance 10.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cp) oxidoreductase activity (Cp) aging (Cp)
extracellular region (Cp)
Anatomy Link Frequency
neurons 3
brain 2
liver 1
hind limb 1
thoracic 1
Cp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 38 100.00 Very High Very High Very High
agonist 18 100.00 Very High Very High Very High
methadone 17 100.00 Very High Very High Very High
Cannabinoid receptor 10 100.00 Very High Very High Very High
Lasting pain 8 100.00 Very High Very High Very High
Prostatitis 8 100.00 Very High Very High Very High
MU agonist 6 100.00 Very High Very High Very High
central pain 5 100.00 Very High Very High Very High
Multiple sclerosis 4 100.00 Very High Very High Very High
Substantia nigra 3 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Pancreatitis 39 100.00 Very High Very High Very High
Infection 36 100.00 Very High Very High Very High
Pain 24 100.00 Very High Very High Very High
Reprotox - General 1 9 100.00 Very High Very High Very High
Demyelinating Disease 4 100.00 Very High Very High Very High
Cytomegalovirus Infection 3 100.00 Very High Very High Very High
Chlamydia Infection 2 100.00 Very High Very High Very High
Cognitive Disorder 3 99.82 Very High Very High Very High
Hematologic Neoplasms 3 99.32 Very High Very High Very High
Disease 10 97.72 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Fever had no systematic effect on Cp.
Neg (no) Regulation (effect) of Cp
1) Confidence 0.53 Published 2003 Journal Anesthesiology Section Body Doc Link 14508328 Disease Relevance 0 Pain Relevance 0
The results of these studies also suggest an important role for continuing education on the diagnosis and treatment of CP.
Regulation (role) of CP associated with prostatitis
2) Confidence 0.37 Published 2009 Journal Andrologia Section Abstract Doc Link 19737274 Disease Relevance 0.87 Pain Relevance 0.40
It is concluded that omeprazole causes an increase in the bioavailability of oral RS-methadone without modifying the analgesic response but affecting the Cp-effect relationship.
Neg (without) Regulation (affecting) of Cp associated with analgesic, methadone and bioavailability
3) Confidence 0.27 Published 2002 Journal J Pharm Sci Section Abstract Doc Link 12115824 Disease Relevance 0 Pain Relevance 1.29
In total, 24/44 (55%) patients were positive for Cp nucleic acid in any PCR.
Regulation (positive) of Cp
4) Confidence 0.27 Published 2006 Journal Scand. J. Infect. Dis. Section Abstract Doc Link 16938728 Disease Relevance 0.48 Pain Relevance 0.08
A small minority of people may have other factors causing their gastritis, bile reflux, or anti-inflammatory drugs, for example, CP causes temporary dyspeptic symptoms when an individual receives an acute infection for the first time, but what is much less certain is whether or not CP is responsible for chronic dyspeptic symptoms, and whether eradication of CP will improve dyspepsia.
Spec (whether) Regulation (responsible) of CP in bile associated with bile, inflammation, cinod, nud, gastritis and infection
5) Confidence 0.26 Published 1989 Journal J. Clin. Gastroenterol. Section Abstract Doc Link 2809137 Disease Relevance 0.88 Pain Relevance 0.23
BACKGROUND: The aim of our study was to investigate the influence of prior cytomegalovirus (CMV) or Chlamydia pneumoniae (CP) infection on prognosis after percutaneous coronary intervention (PCI).
Spec (investigate) Regulation (influence) of CP associated with cytomegalovirus infection, chlamydia infection and infection
6) Confidence 0.18 Published 2004 Journal Am. Heart J. Section Abstract Doc Link 15459599 Disease Relevance 0.62 Pain Relevance 0.07
No significant effect of the CP treatment on corticosterone levels was found.
Neg (No) Regulation (effect) of CP
7) Confidence 0.18 Published 2003 Journal Psychopharmacology (Berl.) Section Body Doc Link 12955302 Disease Relevance 0 Pain Relevance 0
Alterations in enkephalin expression in the substantia nigra and CP in response to ethanol exposure could be involved in the mechanisms underlying brain sensitivity to the drug.
Regulation (Alterations) of CP in brain associated with substantia nigra and enkephalin
8) Confidence 0.17 Published 2008 Journal J. Mol. Neurosci. Section Abstract Doc Link 18227978 Disease Relevance 0 Pain Relevance 0.38
Examination of the effect of the cannabinoid receptor agonist, CP 55,940, on electrically evoked transmitter release from rat brain slices.
Regulation (effect) of CP in brain associated with cannabinoid receptor, analgesic and agonist
9) Confidence 0.14 Published 1997 Journal Eur. J. Pharmacol. Section Title Doc Link 9145770 Disease Relevance 0 Pain Relevance 0.47
Involvement of the kappa-opioid receptor in the anxiogenic-like effect of CP 55,940 in male rats.
Regulation (effect) of CP associated with cannabinoid and kappa opioid receptor
10) Confidence 0.14 Published 2003 Journal Pharmacol. Biochem. Behav. Section Title Doc Link 12543231 Disease Relevance 0.15 Pain Relevance 0.49
We provide the first pharmacological evidence about the involvement of the kappa-opioid receptor in the anxiogenic-like effect of CP 55,940.
Regulation (effect) of CP associated with kappa opioid receptor
11) Confidence 0.14 Published 2003 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 12543231 Disease Relevance 0.16 Pain Relevance 0.41
Two patterns of expression were evident with one set of proteins regulated at both the transcript and protein levels (Cp, Lgals3, Fgf2, and Stat3) (Figure 5) and another set with altered protein expression but no significant changes in transcript expression (Cryaa, Cryab, Cryba3, Crybb2, Dbi, and Anxa5) (Figure 6).
Regulation (regulated) of Cp
12) Confidence 0.11 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020973 Disease Relevance 0 Pain Relevance 0
This trend may affect the CP-related high risk of infection due to the increased incidence of neutropenia in patients with a CP (13, 14).
Spec (may) Regulation (affect) of CP associated with neutropenia and infection
13) Confidence 0.11 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2995228 Disease Relevance 1.47 Pain Relevance 0
The selective CB1 cannabinoid receptor antagonist SR 141716A, given i.p. 20 min earlier, significantly reduced the memory deficit Pretreatment with eptastigmine, a second generation cholinesterase inhibitor, given orally 100 min before the cannabinoid agonist, relieved the memory impairment without affecting CP 55,940-induced behavioural alterations such as reduced spontaneous motor activity, analgesia and hind limb splaying.
Neg (without) Regulation (affecting) of CP in hind limb associated with cognitive disorder, cannabinoid receptor, cannabinoid, antagonist, agonist and analgesia
14) Confidence 0.10 Published 2000 Journal Neuroreport Section Abstract Doc Link 10884065 Disease Relevance 0.17 Pain Relevance 0.49
Serum ceruloplasmin (CPN) levels under different types of acute and chronic experimentally-induced inflammatory conditions in rats and the effect of anti-inflammatory drugs viz. oxyphenylbutazone and hydrocortisone on serum CPN levels were investigated.
Spec (investigated) Regulation (under) of Serum ceruloplasmin associated with inflammation and cinod
15) Confidence 0.10 Published 1985 Journal Pharmacol Res Commun Section Abstract Doc Link 4048245 Disease Relevance 0.55 Pain Relevance 0.32
Because Ca2+ channels underlie release of transmitters from neurons, the effects of opioid agonists and CP 55,940 on depolarization-evoked release of calcitonin gene-related peptide (CGRP) were compared.
Regulation (effects) of CP in neurons associated with mu agonist and calcitonin gene-related peptide
16) Confidence 0.09 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 14973253 Disease Relevance 0.07 Pain Relevance 1.40
Two bioassays were used to compare the effects of the CB1 receptor agonist CP 55,940 and morphine on dissociated adult rat DRG neurons.
Regulation (effects) of CP in neurons associated with agonist and morphine
17) Confidence 0.09 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 14973253 Disease Relevance 0.07 Pain Relevance 0.69
In the cases where we custom designed PCR primers, the average Cp values were compared to the Cp value of the reference gene glyceraldehyde 3-phosphate dehydrogenase (Gadph), to give us the ?
Regulation (values) of Cp
18) Confidence 0.09 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC3001741 Disease Relevance 0 Pain Relevance 0
However, the obtained images can be operator dependent, and interobserver variability may affect interpretation of CP by EUS.
Spec (may) Regulation (affect) of CP associated with chronic pancreatitis
19) Confidence 0.08 Published 2007 Journal J. Gastroenterol. Section Abstract Doc Link 17238035 Disease Relevance 1.34 Pain Relevance 1.36
To investigate the effect of chronic pancreatitis (CP) on in vitro hepatic sensitivity to insulin, the suppression of glucagon-stimulated hepatic glucose production (HGP) by insulin was examined during isolated liver perfusion (ILP) in CP and sham-operated rats.
Spec (investigate) Regulation (effect) of CP in liver associated with chronic pancreatitis
20) Confidence 0.07 Published 1989 Journal J. Surg. Res. Section Abstract Doc Link 2654478 Disease Relevance 0.53 Pain Relevance 0.49

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