INT276929

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.74
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr6) plasma membrane (Tlr6) intracellular (Tlr6)
Anatomy Link Frequency
macrophage 1
Tlr6 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 27 79.16 Quite High
cytokine 27 16.12 Low Low
chemokine 15 5.00 Very Low Very Low Very Low
Inflammation 12 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Yersinia Infection 3 95.52 Very High Very High Very High
Cancer 243 94.16 High High
Metastasis 138 67.56 Quite High
Brain Tumor 3 60.72 Quite High
Lewis Lung Carcinoma 3 51.04 Quite High
Immunotherapy Of Cancer 6 30.88 Quite Low
Leukemia 3 27.88 Quite Low
Skin Cancer 24 25.08 Quite Low
Death 21 5.00 Very Low Very Low Very Low
Experimental Melanoma 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Also, the TLR2/TLR6 heterodimer is involved in phosphorylation or nuclear translocation of Stat3 induced by macrophage activating lipopeptide-2 or LcrV of Yersinia pestis [28], [29].
Regulation (involved) of TLR6 in macrophage associated with yersinia infection
1) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2716531 Disease Relevance 0.74 Pain Relevance 0.04
Cells were grown in Petri dishes and arrested in medium containing 0.4% serum 6 hours before transfection with 0.2 ┬Ámol/L shRNA targeting TLR2, TLR6 or Dectin-1.
Regulation (targeting) of TLR6
2) Confidence 0.14 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2716531 Disease Relevance 0 Pain Relevance 0
The targeted sequences for the RNAi of mouse TLR2, TLR6, Dectin-1, and control were GGAACAGAGTGGCAACAGT, AGGAACCTTACTCATGTCC, GACAGCTTCCT ATCAAGAA, and GCGAGTAGCGCTAGGAAGT, respectively.
Regulation (control) of TLR6
3) Confidence 0.14 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2716531 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox