INT276947

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Stat3) signal transduction (Stat3) plasma membrane (Stat3)
nucleus (Stat3) DNA binding (Stat3) transcription factor binding (Stat3)
Anatomy Link Frequency
macrophage 2
Gbp6 (Mus musculus)
Stat3 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 9 77.88 Quite High
cytokine 9 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Yersinia Infection 1 99.52 Very High Very High Very High
Cancer 81 92.88 High High
Metastasis 46 66.28 Quite High
Brain Tumor 1 59.44 Quite High
Lewis Lung Carcinoma 1 49.76 Quite Low
Immunotherapy Of Cancer 2 38.88 Quite Low
Skin Cancer 8 23.80 Low Low
Death 7 5.00 Very Low Very Low Very Low
Experimental Melanoma 5 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Also, the TLR2/TLR6 heterodimer is involved in phosphorylation or nuclear translocation of Stat3 induced by macrophage activating lipopeptide-2 or LcrV of Yersinia pestis [28], [29].
macrophage activating lipopeptide-2 Positive_regulation (induced) of Phosphorylation (phosphorylation) of Stat3 in macrophage associated with yersinia infection
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2716531 Disease Relevance 0.70 Pain Relevance 0.04

General Comments

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