INT276948

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Context Info
Confidence 0.25
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.06
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr2, Tlr4) plasma membrane (Tlr2, Tlr4) intracellular (Tlr2, Tlr4)
cytoplasm (Tlr2, Tlr4)
Tlr2 (Mus musculus)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 9 94.76 High High
agonist 2 62.88 Quite High
Fibrosis 1 62.80 Quite High
inflammatory 4 40.32 Quite Low
cytokine 9 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 81 95.88 Very High Very High Very High
Skin Cancer 8 90.44 High High
Metastasis 46 85.88 High High
Death 7 77.76 Quite High
Experimental Melanoma 5 77.08 Quite High
Pulmonary Fibrosis 1 62.80 Quite High
INFLAMMATION 4 40.32 Quite Low
Shock 2 5.00 Very Low Very Low Very Low
Immunotherapy Of Cancer 2 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expressions of TLR2 and TLR4 on B16 cells were significantly inhibited by a corresponding TLR2- or TLR4- shRNA (Figure S1A) and up-regulated by LPS treatment (Figure S1B).
TLR2 Negative_regulation (inhibited) of Gene_expression (expressions) of TLR4
1) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2716531 Disease Relevance 1.06 Pain Relevance 0.14

General Comments

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