INT277064

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.15
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.47
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CRP, TIMP1) extracellular space (CRP) aging (TIMP1)
Anatomy Link Frequency
endothelial cells 2
extracellular matrix 2
CRP (Homo sapiens)
TIMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 16 100.00 Very High Very High Very High
Inflammation 36 89.44 High High
imagery 26 50.00 Quite Low
Angina 16 27.52 Quite Low
cytokine 8 10.56 Low Low
ischemia 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
positron emission tomography 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 36 89.44 High High
Adhesions 6 84.48 Quite High
Rupture 8 81.36 Quite High
Atherosclerotic Plaque 18 79.12 Quite High
Cardiovascular Disease 6 63.52 Quite High
Injury 2 59.76 Quite High
Disease 14 58.76 Quite High
Atherosclerosis 42 50.00 Quite Low
Cv Unclassified Under Development 2 35.08 Quite Low
Myocardial Infarction 38 32.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CRP increased the expression of MMP-1 (collagenase) and MMP-10 (stromelysin-2) by human endothelial cells via kinase pathways.
CRP Positive_regulation (increased) of Gene_expression (expression) of collagenase in endothelial cells
1) Confidence 0.15 Published 2006 Journal Biomark Insights Section Body Doc Link PMC2716784 Disease Relevance 0.76 Pain Relevance 0.24
A novel finding recently reported by our group is that CRP induces endothelial expression of metalloproteinases (MMPs) capable of degrading the extracellular matrix.
CRP Positive_regulation (induces) of Gene_expression (expression) of metalloproteinases in extracellular matrix associated with metalloproteinase
2) Confidence 0.13 Published 2006 Journal Biomark Insights Section Body Doc Link PMC2716784 Disease Relevance 0.71 Pain Relevance 0.21

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox