INT277114

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.93
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (FTO)
Anatomy Link Frequency
fat 1
body 1
FTO (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 104 100.00 Very High Very High Very High
Diabetes Mellitus 73 100.00 Very High Very High Very High
Inflammatory Bowel Disease 16 89.16 High High
Cancer 6 84.80 Quite High
Disease 42 82.24 Quite High
Metabolic Syndrome 3 78.84 Quite High
Aging 1 70.44 Quite High
Breast Cancer 4 68.48 Quite High
Congenital Anomalies 1 27.48 Quite Low
Reprotox - General 1 4 27.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our investigation of the FTO SNP rs9939609 showed no significant association with obesity.
FTO Binding (investigation) of associated with obesity
1) Confidence 0.34 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2958899 Disease Relevance 0.33 Pain Relevance 0
4) of the FTO gene association was found to explain 0.2% of the variance in BMI in the NFBC 1966 cohort.
FTO Binding (association) of associated with obesity
2) Confidence 0.30 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2830824 Disease Relevance 0.58 Pain Relevance 0
Frayling et al. examined the association of the FTO variant with body mass index (BMI) in 13 cohorts with 38,759 participants.
FTO Spec (examined) Binding (association) of in body associated with obesity
3) Confidence 0.22 Published 2007 Journal Biomarker Insights Section Body Doc Link PMC2717811 Disease Relevance 1.47 Pain Relevance 0
For example, one gene associated with T2DM, fat mass and obesity associated gene (FTO) (Scott et al. 2007), also showed an association with obesity-associated quantitative traits in an independent study (Frayling et al. 2007).
FTO Binding (associated) of in fat associated with diabetes mellitus and obesity
4) Confidence 0.16 Published 2007 Journal Biomarker Insights Section Body Doc Link PMC2717811 Disease Relevance 1.56 Pain Relevance 0

General Comments

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