INT277164

Context Info Confidence 0.01 First Reported 2007 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 2.88 Pain Relevance 0.35

cell adhesion (Cdh3) plasma membrane (Cdh3) cytoplasm (Cdh3)

Cdh3 (Mus musculus)

Pain Link Frequency Relevance Heat Piles 2 99.04 metalloproteinase 28 69.88 Nerve growth factor 4 30.00 chemokine 8 5.00 Inflammation 6 5.00 fibrosis 3 5.00 cytokine 2 5.00 corticosteroid 1 5.00 palliative 1 5.00 cINOD 1 5.00

Disease Link Frequency Relevance Heat Cancer 66 99.34 Anorectal Disorders 2 99.04 Lung Cancer 136 98.68 Colitis 52 98.46 Toxicity 20 87.44 Metastasis 9 86.56 Rectal Cancer 6 82.36 Adhesions 8 78.08 Aggression 1 75.04 Abscess 3 69.44

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Other investigators have addressed interesting issues regarding RC pathogenesis, besides morphology, and have reported that transient aberrant expression of P-cadherin may be associated with proctitis [33].

Gene_expression (expression) of P-cadherin associated with colitis and piles

1) Confidence 0.01 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2903531 Disease Relevance 1.62 Pain Relevance 0.05

In fact, MM and serous AC are the two tumors that most strikingly exhibit co-expression of different cadherins, including N-cadherin, P-cadherin and E-cadherin (Sivertsen, 2006a).

Gene_expression (expression) of P-cadherin associated with lung cancer and cancer

2) Confidence 0.01 Published 2007 Journal Biomarker Insights Section Body Doc Link PMC2717840 Disease Relevance 1.26 Pain Relevance 0.30

General Comments

This test has worked.