INT277185

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Context Info
Confidence 0.07
First Reported 2007
Last Reported 2007
Negated 2
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 4.70
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (BIRC7) intracellular (BIRC7) enzyme binding (BIRC7)
cytoplasm (BIRC7)
BIRC7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 3 86.44 High High
metalloproteinase 84 5.00 Very Low Very Low Very Low
chemokine 24 5.00 Very Low Very Low Very Low
Nerve growth factor 12 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 408 99.84 Very High Very High Very High
Solid Tumor 15 97.88 Very High Very High Very High
Apoptosis 69 97.32 Very High Very High Very High
Pleurisy 3 86.84 High High
INFLAMMATION 3 86.44 High High
Death 3 74.40 Quite High
Cancer 168 62.24 Quite High
Neurodegenerative Disease 3 61.64 Quite High
Malignant Neoplastic Disease 33 50.00 Quite Low
Leukemia 3 30.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that XIAP and Survivin, but not Livin, are frequently expressed in MM, and that the reduced nuclear Survivin expression in effusions may be related to lesser degree of proliferation.
Neg (not) Gene_expression (expressed) of Livin associated with lung cancer
1) Confidence 0.07 Published 2007 Journal Biomarker Insights Section Body Doc Link PMC2717840 Disease Relevance 1.52 Pain Relevance 0.03
Using immunoblotting, we detected expression of XIAP and Survivin, but no expression of Livin, in effusion specimens.
Neg (no) Gene_expression (expression) of Livin
2) Confidence 0.07 Published 2007 Journal Biomarker Insights Section Body Doc Link PMC2717840 Disease Relevance 1.52 Pain Relevance 0.04
We recently analyzed the expression of XIAP, Survivin and Livin in MM (Kleinberg, 2007).
Spec (analyzed) Gene_expression (expression) of Livin associated with lung cancer
3) Confidence 0.05 Published 2007 Journal Biomarker Insights Section Body Doc Link PMC2717840 Disease Relevance 1.67 Pain Relevance 0.04

General Comments

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