INT277257

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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.51
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Satb2) DNA binding (Satb2) cytoplasm (Satb2)
Anatomy Link Frequency
jaw 1
Satb2 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 3 98.72 Very High Very High Very High
Syndrome 48 97.52 Very High Very High Very High
Hyperplasia 3 94.96 High High
Congenital Anomalies 21 93.92 High High
Epilepsy 3 91.84 High High
Intellectual Impairment 39 91.44 High High
Cleft Palate 42 91.12 High High
Osteoporosis 6 90.28 High High
Learning Disorders 9 89.60 High High
Language Development Disorders 9 87.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Special AT-rich sequence binding protein 2 (SATB2; OMIM 608148) is a DNA-binding protein that regulates gene expression through chromatin modification and interaction with other proteins and plays roles in mammalian development [1]–[4].
SATB2 Binding (interaction) of
1) Confidence 0.37 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2719055 Disease Relevance 0.63 Pain Relevance 0
Three individuals with apparently balanced translocations with a breakpoint within SATB2 or in a highly conserved region 3?
SATB2 Binding (breakpoint) of
2) Confidence 0.37 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2719055 Disease Relevance 1.05 Pain Relevance 0
Loss of Satb2 correlates with increased cell death in the developing jaw along with altered expression of other craniofacial developmental genes [10].
Satb2 Binding (Loss) of in jaw associated with death
3) Confidence 0.33 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2719055 Disease Relevance 0.84 Pain Relevance 0

General Comments

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