INT277371

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Context Info
Confidence 0.72
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.97
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (LDHB) mitochondrion (LDHB) small molecule metabolic process (LDHB)
oxidoreductase activity (LDHB) cytoplasm (LDHB)
LDHB (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 83 91.08 High High
Insulin Resistance 12 71.76 Quite High
Frailty 2 68.08 Quite High
Aging 1 59.80 Quite High
Appetite Loss 1 59.40 Quite High
Disease 9 52.04 Quite High
Obesity 4 40.08 Quite Low
Muscle Weakness 1 27.28 Quite Low
Toxicity 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since mitochondrial oxidative phosphorylation and LDHB in a way compete for same pool of pyruvate it is also a possibility that decreased levels of LDHB is a compensatory mechanism in response to impaired mitochondrial function as more pyruvate will be available for acetyl Coenzyme A conversion.


Phosphorylation (phosphorylation) of LDHB
1) Confidence 0.72 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2719801 Disease Relevance 0.97 Pain Relevance 0

General Comments

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