INT277461

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.47
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Fgf8) extracellular space (Fgf8) extracellular region (Fgf8)
Anatomy Link Frequency
mesoderm 6
Fgf8 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 249 91.36 High High
midbrain 60 83.12 Quite High
chemokine 6 68.72 Quite High
Action potential 12 9.40 Low Low
gABA 9 5.00 Very Low Very Low Very Low
Glutamate 9 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
drug abuse 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nervous System Malformation 3 80.64 Quite High
Neurodegenerative Disease 21 74.56 Quite High
Disease 9 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Parkinson's Disease 3 5.00 Very Low Very Low Very Low
Mucocutaneous Lymph Node Syndrome 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Drug Dependence 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nonetheless the introduction of FGF10 to chick embryos up-regulated FGF8 expression in the ectoderm through Wnt3a signaling and stimulated SHH expression in the posterior mesoderm followed by outgrowth initiation of chick limb structures [48], [49].
Positive_regulation (-) of Gene_expression (expression) of FGF8 in mesoderm
1) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2719871 Disease Relevance 0.16 Pain Relevance 0.35
Nonetheless the introduction of FGF10 to chick embryos up-regulated FGF8 expression in the ectoderm through Wnt3a signaling and stimulated SHH expression in the posterior mesoderm followed by outgrowth initiation of chick limb structures [48], [49].
Positive_regulation (regulated) of Gene_expression (expression) of FGF8 in mesoderm
2) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2719871 Disease Relevance 0.16 Pain Relevance 0.35
Nonetheless the introduction of FGF10 to chick embryos up-regulated FGF8 expression in the ectoderm through Wnt3a signaling and stimulated SHH expression in the posterior mesoderm followed by outgrowth initiation of chick limb structures [48], [49].
Positive_regulation (up) of Gene_expression (expression) of FGF8 in mesoderm
3) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2719871 Disease Relevance 0.16 Pain Relevance 0.35

General Comments

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