INT277596

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Context Info
Confidence 0.61
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Hdac1) nucleus (Hdac1) enzyme binding (Hdac1)
DNA binding (Hdac1) protein complex (Hdac1) transcription factor binding (Hdac1)
Hdac1 (Mus musculus)
Pain Link Frequency Relevance Heat
depression 1 26.88 Quite Low
cocaine 4 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Acute pain 2 5.00 Very Low Very Low Very Low
Eae 2 5.00 Very Low Very Low Very Low
nociceptor 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Neuronal excitability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertrophy 3 90.20 High High
Repression 8 87.20 High High
Targeted Disruption 7 67.88 Quite High
Convulsion 27 52.48 Quite High
Nociception 9 50.00 Quite Low
Depression 1 26.88 Quite Low
Epilepsy 4 13.36 Low Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Muscular Spasm 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Extensive deletion analysis and in vitro transfection studies have also identified the minimum N-terminal protein domains of the HDAC4 protein sufficient to interact with binding proteins for nucleo-cytoplasmic trafficking, phosphorylation and recruitment of HDAC1 [4], [8], [12]–[14], [16]–[19].
Phosphorylation (phosphorylation) of HDAC1
1) Confidence 0.61 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2720538 Disease Relevance 0.59 Pain Relevance 0

General Comments

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