INT277615

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Context Info
Confidence 0.38
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ZNF238, Hdac3) DNA binding (ZNF238, Hdac3) nuclear chromosome (ZNF238)
intracellular (ZNF238) cytoplasm (Hdac3)
ZNF238 (Homo sapiens)
Hdac3 (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 4 77.68 Quite High
Spinal cord 3 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Acute pain 2 5.00 Very Low Very Low Very Low
Eae 2 5.00 Very Low Very Low Very Low
nociceptor 2 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Neuronal excitability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 8 63.48 Quite High
Convulsion 27 50.00 Quite Low
Nociception 9 50.00 Quite Low
Hypertrophy 3 11.12 Low Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Epilepsy 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Muscular Spasm 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The integrity of the catalytic domain of HDAC4 is necessary for recruiting the HDAC3 N-CoR repressor complex and for subsequent deacetylase activity of the complex, but the deacetylase activity of HDAC4 is at best minimal [9], [11].
Positive_regulation (necessary) of repressor Binding (complex) of HDAC3
1) Confidence 0.38 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2720538 Disease Relevance 0.06 Pain Relevance 0.07

General Comments

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