INT277669

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.46
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Cyp3a11) endoplasmic reticulum (Cyp3a11)
Cyp3a11 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 2 65.68 Quite High
pruritus 5 32.96 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Onset of action 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 1 95.60 Very High Very High Very High
Proteinuria 1 82.48 Quite High
Disease 21 80.48 Quite High
Lymphatic System Cancer 51 77.80 Quite High
Sudden Death 1 70.08 Quite High
Vomiting 10 67.24 Quite High
Thrombocytopenia 10 66.60 Quite High
Pulmonary Embolism 1 65.68 Quite High
Fatigue 10 64.68 Quite High
Chills 1 61.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is not an inhibitor of CYP drug metabolizing enzymes but there is potential for suppression of CYP2C9 and CYP3A at concentrations above 10 ?
Positive_regulation (potential) of Negative_regulation (suppression) of CYP3A
1) Confidence 0.09 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721288 Disease Relevance 1.46 Pain Relevance 0.03

General Comments

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