INT277691

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Cdkn1a, Casp3) cytosol (Cdkn1a, Casp3) nucleus (Cdkn1a, Casp3)
mitochondrion (Casp3) intracellular (Casp3) peptidase activity (Casp3)
Cdkn1a (Mus musculus)
Casp3 (Mus musculus)
Pain Link Frequency Relevance Heat
pruritus 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Onset of action 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 17 93.20 High High
Cancer 58 92.60 High High
Lymphatic System Cancer 51 90.96 High High
Mycosis Fungoides 48 76.60 Quite High
Syndrome 31 76.48 Quite High
Death 8 56.96 Quite High
Multiple Myeloma 1 35.64 Quite Low
Leukemia 2 34.92 Quite Low
Skin Cancer 1 34.52 Quite Low
Neuroblastoma 2 34.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This was associated with an accumulation of acetylated histones, increased p21WAF1 and bax, decreased Stat6 and phosphor-Stat6, and activation of caspase 3 (Zhang et al 2005).
p21WAF1 Negative_regulation (decreased) of Positive_regulation (activation) of caspase 3
1) Confidence 0.00 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721288 Disease Relevance 1.01 Pain Relevance 0

General Comments

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