INT27774

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Context Info
Confidence 0.68
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 13
Total Number 15
Disease Relevance 12.86
Pain Relevance 4.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Tst) RNA binding (Tst) plasma membrane (Tst)
Anatomy Link Frequency
CPA 2
blood 1
brain 1
Tst (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 20 99.98 Very High Very High Very High
Morphine 32 99.68 Very High Very High Very High
narcan 23 99.62 Very High Very High Very High
rheumatoid arthritis 9 98.40 Very High Very High Very High
spinal inflammation 9 98.12 Very High Very High Very High
Arthritis 3 94.88 High High
antagonist 7 87.04 High High
nud 2 84.16 Quite High
Locus ceruleus 1 84.00 Quite High
headache 2 66.68 Quite High
Disease Link Frequency Relevance Heat
Mycobacterial Infection 637 99.64 Very High Very High Very High
Rheumatoid Arthritis 21 98.40 Very High Very High Very High
Low Back Pain 9 98.12 Very High Very High Very High
Latent Tuberculosis 26 97.68 Very High Very High Very High
Hirsutism 62 96.52 Very High Very High Very High
Uterine Hemorrhage 2 95.28 Very High Very High Very High
Seronegative Spondarthritis 3 94.88 High High
Hyperkalemia 4 93.60 High High
Anuria 2 92.00 High High
Renal Insufficiency 4 91.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Central administration of naloxone was without effect in controls but produced a 5-6 degree C rise of TST in the morphine-dependent rat while central administration of 10 microliters of the saline vehicle produced no changes in TST in either group.
Gene_expression (produced) of TST associated with narcan and morphine
1) Confidence 0.68 Published 1989 Journal Brain Res. Section Abstract Doc Link 2670064 Disease Relevance 0.22 Pain Relevance 0.64
RESULTS: TST positivity was approximately 9% in both MMT and BMT settings (p = .27).
Gene_expression (positivity) of TST
2) Confidence 0.53 Published 2009 Journal Am J Drug Alcohol Abuse Section Body Doc Link 20014914 Disease Relevance 0 Pain Relevance 0
A threshold dose of 20 micrograms/0.4 microliters (10 micrograms/0.2 microliters, bilaterally) of naloxone was identified to produce this surge in TST in all three brain regions.
Gene_expression (produce) of TST in brain associated with narcan
3) Confidence 0.53 Published 1987 Journal Brain Res. Bull. Section Abstract Doc Link 3651842 Disease Relevance 0.08 Pain Relevance 0.76
Administration of 5 or 10 micrograms of the LH-RH agonist (Des-Gly10, [im-Bzl-D-His6]LH-RH ethylamide) into the LV produced a significantly greater elevation in TST (4 degrees C) in the morphine-dependent rats compared to a negligible rise in TST in the control rats; however, administration of a larger dose of 20 micrograms of the LH-RH agonist produced similar TST responses of about 4 degrees C in both groups.
Gene_expression (produced) of TST associated with agonist and morphine
4) Confidence 0.46 Published 1989 Journal Brain Res. Section Abstract Doc Link 2670064 Disease Relevance 0.05 Pain Relevance 0.93
Administration of 5 or 10 micrograms of the LH-RH agonist (Des-Gly10, [im-Bzl-D-His6]LH-RH ethylamide) into the LV produced a significantly greater elevation in TST (4 degrees C) in the morphine-dependent rats compared to a negligible rise in TST in the control rats; however, administration of a larger dose of 20 micrograms of the LH-RH agonist produced similar TST responses of about 4 degrees C in both groups.
Gene_expression (produced) of TST associated with agonist and morphine
5) Confidence 0.46 Published 1989 Journal Brain Res. Section Abstract Doc Link 2670064 Disease Relevance 0.18 Pain Relevance 0.89
At the homeless clinic, among patients tested by IGRA, a positive or negative result was obtained in 99%, which is greater than the proportion of patients who returned for TST reading at that particular site prior to IGRA implementation (88%).
Gene_expression (reading) of TST
6) Confidence 0.45 Published 2006 Journal BMC Infect Dis Section Body Doc Link PMC1434750 Disease Relevance 0.57 Pain Relevance 0
Standard case definitions for a report of a verified case of tuberculosis (RVCT) were used. [12] Medical records were also reviewed for available TST results from within 30 days of the IGRA date

Acceptability of blood-test based TB screening

Gene_expression (results) of TST in blood associated with mycobacterial infection
7) Confidence 0.45 Published 2006 Journal BMC Infect Dis Section Body Doc Link PMC1434750 Disease Relevance 1.12 Pain Relevance 0
No significant difference was observed for TST positivity (TST > or = 5 mm) between the patients with RA and AS (p = 0.101).
Gene_expression (positivity) of TST associated with spinal inflammation and rheumatoid arthritis
8) Confidence 0.35 Published 2008 Journal Clin. Rheumatol. Section Abstract Doc Link 18320137 Disease Relevance 1.42 Pain Relevance 0.47
Similarly, no significant difference was also observed for TST positivity between the patients who received immunosuppressive therapy and those who did not (p = 0.154).
Gene_expression (positivity) of TST
9) Confidence 0.35 Published 2008 Journal Clin. Rheumatol. Section Abstract Doc Link 18320137 Disease Relevance 1.28 Pain Relevance 0.45
No significant difference was observed for TST positivity (TST > or = 5 mm) between the patients with RA and AS (p = 0.101).
Gene_expression (positivity) of TST associated with spinal inflammation and rheumatoid arthritis
10) Confidence 0.35 Published 2008 Journal Clin. Rheumatol. Section Abstract Doc Link 18320137 Disease Relevance 1.42 Pain Relevance 0.47
40) (Table 4), the risk of developing TB given a positive TST response increased slightly.
Gene_expression (response) of TST associated with mycobacterial infection
11) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2865542 Disease Relevance 1.35 Pain Relevance 0
When adjusting on age, sex and proximity to case, all factors independently associated with development of TB in contacts of TB cases [15], the hazard of developing TB was 1.5 greater when TST response was >10 mm and 2.6 greater when TST response was >15 mm.
Gene_expression (response) of TST associated with mycobacterial infection
12) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2865542 Disease Relevance 0.95 Pain Relevance 0
When adjusting on age, sex and proximity to case, all factors independently associated with development of TB in contacts of TB cases [15], the hazard of developing TB was 1.5 greater when TST response was >10 mm and 2.6 greater when TST response was >15 mm.
Gene_expression (response) of TST associated with mycobacterial infection
13) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2865542 Disease Relevance 0.95 Pain Relevance 0
It produces a decrease in circulating Tst and androstenedione levels through a reduction in circulating LH and has been used as an effective treatment for hirsutism.[21] CPA is available in combination with ethinyl estradiol (EE) (2 mg CPA and 35 ?
Gene_expression (levels) of Tst in CPA associated with hirsutism
14) Confidence 0.08 Published 2010 Journal Indian Journal of Dermatology Section Body Doc Link PMC2856356 Disease Relevance 1.63 Pain Relevance 0.11
It produces a decrease in circulating Tst and androstenedione levels through a reduction in circulating LH and has been used as an effective treatment for hirsutism.[21] CPA is available in combination with ethinyl estradiol (EE) (2 mg CPA and 35 ?
Gene_expression (androstenedione) of Tst in CPA associated with hirsutism
15) Confidence 0.08 Published 2010 Journal Indian Journal of Dermatology Section Body Doc Link PMC2856356 Disease Relevance 1.63 Pain Relevance 0.11

General Comments

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