INT277765

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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.55
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (BCR, Abl1) kinase activity (BCR, Abl1) mitochondrion (Abl1)
DNA binding (Abl1) cytoplasm (Abl1) signal transduction (BCR)
BCR (Homo sapiens)
Abl1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 2 69.44 Quite High
Antihistamine 1 11.72 Low Low
pruritus 1 5.68 Low Low
aspirin 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
palliative 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloid Leukemia 20 99.06 Very High Very High Very High
Myelofibrosis 28 98.40 Very High Very High Very High
Myelodysplastic Syndromes 60 92.12 High High
Toxicity 4 85.04 High High
Chronic Myelomonocytic Leukemia 15 81.72 Quite High
Genetic Translocation 1 69.92 Quite High
Leukemia 6 64.72 Quite High
Injury 1 51.16 Quite High
Serositis 1 50.12 Quite High
Pressure And Volume Under Development 1 49.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The first is that the clinical phenotype of PMF can resemble closely that of CML, indeed in some patients only the presence or absence of the BCR-ABL is a reliable marker to distinguish these entities.
BCR Neg (absence) Binding (absence) of ABL associated with myeloid leukemia and myelofibrosis
1) Confidence 0.18 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721304 Disease Relevance 1.55 Pain Relevance 0.03

General Comments

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