INT277786

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Context Info
Confidence 0.29
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgal)
Anatomy Link Frequency
lymphocytes 2
Itgal (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 3 67.28 Quite High
Inflammation 6 65.84 Quite High
psoriasis 44 25.84 Quite Low
Arthritis 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Adalimumab 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Psoriasis 50 84.08 Quite High
Disease 4 74.80 Quite High
INFLAMMATION 7 65.84 Quite High
Adhesions 5 33.88 Quite Low
Hyperplasia 1 28.80 Quite Low
Arthritis 3 5.00 Very Low Very Low Very Low
Thrombocytopenia 3 5.00 Very Low Very Low Very Low
Pruritus 3 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Complete saturation and maintenance of CD11a binding site down-regulation on lymphocytes required weekly intravenous doses of 0.6 mg/kg, which corresponds to an efalizumab plasma concentration of 5 ?
Negative_regulation (maintenance) of CD11a Binding (binding) of in lymphocytes
1) Confidence 0.29 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721316 Disease Relevance 0.22 Pain Relevance 0.07

General Comments

This test has worked.

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