INT277809

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Context Info
Confidence 0.15
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD4, CD40LG) extracellular space (CD40LG) signal transduction (CD4)
extracellular region (CD40LG) cell adhesion (CD4) enzyme binding (CD4)
Anatomy Link Frequency
NK cells 2
T-cells 2
CD4 (Homo sapiens)
CD40LG (Homo sapiens)
Pain Link Frequency Relevance Heat
withdrawal 4 28.64 Quite Low
fibrosis 8 11.04 Low Low
tolerance 32 5.00 Very Low Very Low Very Low
abatacept 12 5.00 Very Low Very Low Very Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
cva 8 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
psoriasis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 4 41.84 Quite Low
Death 32 23.20 Low Low
Renal Disease 40 22.80 Low Low
Nephrotoxicity 8 20.12 Low Low
Injury 8 16.36 Low Low
Fibrosis 8 11.04 Low Low
Hyalinosis 4 9.12 Low Low
Hypertension 20 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 20 5.00 Very Low Very Low Very Low
Infection 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CD40 is expressed on all APCs (including B cells) and its ligand (CD40L or CD154) is on activated CD4+ T-cells and on a subset of CD8+ T-cells and NK cells.
CD4 Binding (ligand) of CD154 in T-cells
1) Confidence 0.15 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721321 Disease Relevance 0 Pain Relevance 0
CD40 is expressed on all APCs (including B cells) and its ligand (CD40L or CD154) is on activated CD4+ T-cells and on a subset of CD8+ T-cells and NK cells.
CD4 Binding (ligand) of CD40L in T-cells
2) Confidence 0.15 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721321 Disease Relevance 0 Pain Relevance 0
CD40 is expressed on all APCs (including B cells) and its ligand (CD40L or CD154) is on activated CD4+ T-cells and on a subset of CD8+ T-cells and NK cells.
CD4 Binding (ligand) of CD40L in NK cells
3) Confidence 0.05 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721321 Disease Relevance 0 Pain Relevance 0
CD40 is expressed on all APCs (including B cells) and its ligand (CD40L or CD154) is on activated CD4+ T-cells and on a subset of CD8+ T-cells and NK cells.
CD4 Binding (ligand) of CD154 in NK cells
4) Confidence 0.05 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721321 Disease Relevance 0 Pain Relevance 0

General Comments

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