INT27788

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Context Info
Confidence 0.55
First Reported 1980
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.17
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Gnrh1) extracellular region (Gnrh1) molecular_function (Gnrh1)
Anatomy Link Frequency
plasma 2
Gnrh1 (Rattus norvegicus)
LH (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 2 100.00 Very High Very High Very High
Morphine 10 99.40 Very High Very High Very High
narcan 5 97.24 Very High Very High Very High
dexamethasone 7 96.48 Very High Very High Very High
opiate 2 91.52 High High
antagonist 2 84.48 Quite High
Opioid 1 72.24 Quite High
Intracerebroventricular 1 30.28 Quite Low
Disease Link Frequency Relevance Heat
Body Weight 2 93.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GnRH induced a significant (P less than 0.001) increase in serum concentrations of LH in all groups.
GnRH Positive_regulation (induced) of Positive_regulation (increase) of LH
1) Confidence 0.55 Published 1989 Journal J. Endocrinol. Section Abstract Doc Link 2671240 Disease Relevance 0.17 Pain Relevance 0.48
Increase in the serum LH induced by exogenous LHRH was slightly potentiated and not inhibited by a large dose of morphine, in both intact and castrated rats.
LHRH Positive_regulation (induced) of Positive_regulation (Increase) of serum LH associated with morphine
2) Confidence 0.39 Published 1980 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 6776920 Disease Relevance 0 Pain Relevance 1.00
The results show that CDP-choline can increase plasma ACTH and produce additional increases in serum levels of TSH, GH and LH stimulated by TRH, clonidine and LHRH, respectively.
LHRH Positive_regulation (stimulated) of Positive_regulation (increases) of LH in plasma associated with clonidine
3) Confidence 0.25 Published 2004 Journal Fundam Clin Pharmacol Section Abstract Doc Link 15482372 Disease Relevance 0 Pain Relevance 0.24

General Comments

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