INT277884

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.95
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Tas2r111-ps2 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 36 98.16 Very High Very High Very High
Spinal cord 6 22.00 Low Low
Antihistamine 12 5.00 Very Low Very Low Very Low
corticosteroid 9 5.00 Very Low Very Low Very Low
intrathecal 6 5.00 Very Low Very Low Very Low
carpal tunnel syndrome 3 5.00 Very Low Very Low Very Low
abdominal pain 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 84 98.28 Very High Very High Very High
Death 12 88.12 High High
Mucopolysaccharidoses 21 82.72 Quite High
Fabry Disease 3 81.64 Quite High
Gauchers Disease 6 81.04 Quite High
Lifespan 3 67.68 Quite High
Heart Disease 6 60.08 Quite High
Rare Diseases 6 56.36 Quite High
Macrocephaly 6 45.20 Quite Low
Multiple Sulfatase Deficiency Disease 3 33.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Symptoms associated with severe MPS II are usually recognized earlier than those the attenuated phenotype.
MPS II Binding (recognized) of
1) Confidence 0.09 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721351 Disease Relevance 0.47 Pain Relevance 0.11
Its exact function is unclear; however, pathogenic structural rearrangements between IDS2 and IDS have been identified in individuals with MPS II.
MPS II Binding (individuals) of
2) Confidence 0.07 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721351 Disease Relevance 0.06 Pain Relevance 0
Two clinical forms of MPS II have been historically recognized, attenuated and severe, which were primarily distinguished by the presence of CNS involvement.
MPS II Binding (recognized) of associated with central nervous system
3) Confidence 0.07 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721351 Disease Relevance 0.42 Pain Relevance 0.08

General Comments

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