INT277886

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Context Info
Confidence 0.73
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 1.09
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lysosome (Ids)
Ids (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 141 90.56 High High
Thalamus 27 89.04 High High
cerebral cortex 6 44.84 Quite Low
Spinal cord 4 39.48 Quite Low
Inflammatory response 3 24.64 Low Low
Inflammation 3 7.60 Low Low
Neurobehavioral 12 5.00 Very Low Very Low Very Low
Antihistamine 8 5.00 Very Low Very Low Very Low
corticosteroid 6 5.00 Very Low Very Low Very Low
intrathecal 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Gliosis 6 95.16 Very High Very High Very High
Apoptosis 12 94.12 High High
Disease 71 92.24 High High
Rare Diseases 4 73.84 Quite High
Lysosomal Storage Diseases 15 67.12 Quite High
Mucopolysaccharidosis Ii 15 60.60 Quite High
Mucopolysaccharidoses 14 59.28 Quite High
Pathologic Constriction 2 48.20 Quite Low
Death 14 44.16 Quite Low
Spinal Cord Compression 2 39.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunofluorescence analyses were carried out for the detection of NeuN, GFAPĀ and CD68 (36,37) and for the co-localization signal of Lamp2-hIDS.
Localization (localization) of IDS
1) Confidence 0.73 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2989894 Disease Relevance 0.09 Pain Relevance 0
(B) Co-localization of the lysosomal marker Lamp-2 (anti-Lamp2 antibody) and the IDS protein (anti-hIDS antibody) as seen in the merge, as indicated.
Localization (localization) of IDS protein
2) Confidence 0.71 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2989894 Disease Relevance 0.19 Pain Relevance 0.20
(B) Co-localization of the lysosomal marker Lamp-2 (anti-Lamp2 antibody) and the IDS protein (anti-hIDS antibody) as seen in the merge, as indicated.
Localization (localization) of IDS
3) Confidence 0.68 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2989894 Disease Relevance 0.19 Pain Relevance 0.20
The disorder results from mutations in IDS, which is located at Xq28.
Localization (located) of IDS
4) Confidence 0.60 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721351 Disease Relevance 0.54 Pain Relevance 0.09
IDS, which is located at Xq28, spans approximately 24 kb, consists of 9 exons and 8 introns, and has a coding sequence of 2.3 kb.
Localization (located) of IDS
5) Confidence 0.60 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721351 Disease Relevance 0.07 Pain Relevance 0

General Comments

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