INT277913

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Context Info
Confidence 0.60
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (PIGA) biosynthetic process (PIGA)
PIGA (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 17 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Paroxysmal Nocturnal Hemoglobinuria 158 99.80 Very High Very High Very High
Congenital Anomalies 5 99.60 Very High Very High Very High
Disease 25 59.72 Quite High
Syndrome 3 51.60 Quite High
Thrombosis 24 48.40 Quite Low
Convulsion 1 47.20 Quite Low
Hemolysis 55 44.00 Quite Low
Hematological Disease 14 10.36 Low Low
Cv General 3 Under Development 16 5.00 Very Low Very Low Very Low
Aplastic Anemia 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All mutations identified in PNH patients affect the PIG-A gene; no abnormalities were found in any of the other numerous genes involved in the subsequent metabolic steps of the GPI-anchor synthesis.
Regulation (affect) of PIG-A associated with congenital anomalies and paroxysmal nocturnal hemoglobinuria
1) Confidence 0.60 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721357 Disease Relevance 0.49 Pain Relevance 0

General Comments

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