INT277927

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.23
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SMAD4) intracellular (SMAD4) protein binding transcription factor activity (SMAD4)
DNA binding (SMAD4) cytoplasm (SMAD4) cytosol (SMAD4)
WIF1 (Homo sapiens)
SMAD4 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 13 36.24 Quite Low
cINOD 7 5.00 Very Low Very Low Very Low
COX2 3 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 26 97.64 Very High Very High Very High
Stress 2 78.44 Quite High
Hypoxia 1 78.16 Quite High
Cancer 8 64.04 Quite High
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Stomach Cancer 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Gastrointestinal Disease 1 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
QPCR demonstrated specific upregulation in coxP cells of WIF1, a physiological inhibitor of the pathway (Taniguchi et al 2005), of SMAD4, which counteracts WNT signaling (Gregorieff and Clevers 2005), of TLE1 (groucho), a repressor of ?
WIF1 Negative_regulation (inhibitor) of SMAD4
1) Confidence 0.23 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721360 Disease Relevance 0.37 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox