INT278022

Context Info Confidence 0.21 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.27 Pain Relevance 0.03

plasma membrane (Bmpr2) kinase activity (Bmpr2) cytoplasm (Bmpr2)

Bmpr2 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 1 61.68 Pain 3 5.00 Inflammatory response 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Fracture Healing 32 76.88 Osteoporosis 7 64.80 Injury 18 5.00 Tibial Fractures 12 5.00 Malignant Neoplastic Disease 6 5.00 Infection 6 5.00 Pressure Volume 2 Under Development 4 5.00 Pain 3 5.00 Osteogenic Sarcomas 3 5.00 Wound Healing 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

After binding BMP-2, the type II receptor kinase phosphorylates the type I receptor, generating an intracellular response.

Phosphorylation (phosphorylates) of BMP-2

1) Confidence 0.21 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721393 Disease Relevance 0.27 Pain Relevance 0.03

General Comments

This test has worked.