INT278140

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Jak3) intracellular (Jak3) kinase activity (Jak3)
cytoplasm (Jak3)
Jak3 (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 2 81.68 Quite High
Inflammation 21 81.08 Quite High
Arthritis 10 40.16 Quite Low
cytokine 11 34.12 Quite Low
rheumatoid arthritis 5 15.68 Low Low
Bioavailability 4 5.00 Very Low Very Low Very Low
psoriasis 3 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 20 81.08 Quite High
Hypersensitivity 6 74.80 Quite High
Pressure And Volume Under Development 5 66.32 Quite High
Organ Transplantation 4 53.24 Quite High
Autoimmune Disease 12 51.96 Quite High
Targeted Disruption 3 43.68 Quite Low
Severe Combined Immunodeficiency 2 42.72 Quite Low
Arthritis 10 40.16 Quite Low
Rheumatoid Arthritis 5 15.68 Low Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PF-956980, a structurally close analog of CP-690550, has been reported to be a potent and selective inhibitor of JAK3 with IC50?
Regulation (reported) of Negative_regulation (inhibitor) of JAK3
1) Confidence 0.21 Published 2008 Journal Purinergic Signal Section Body Doc Link PMC2721774 Disease Relevance 0.43 Pain Relevance 0.11

General Comments

This test has worked.

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