INT278154

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Syk) plasma membrane (Syk) cytoplasm (Syk)
Syk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 21 96.68 Very High Very High Very High
Arthritis 10 93.72 High High
rheumatoid arthritis 5 83.28 Quite High
psoriasis 3 81.52 Quite High
Potency 2 14.80 Low Low
cytokine 11 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 5 97.48 Very High Very High Very High
INFLAMMATION 20 96.68 Very High Very High Very High
Autoimmune Disease 12 96.00 Very High Very High Very High
Arthritis 10 93.72 High High
Rheumatoid Arthritis 5 83.28 Quite High
Psoriasis 3 81.52 Quite High
Organ Transplantation 4 80.64 Quite High
Immune System Diseases 1 78.08 Quite High
Pressure And Volume Under Development 5 22.52 Low Low
Hypersensitivity 6 18.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A number of drugs targeting the kinases p38, JNK, MEK, IKK2, JAK3, Lck, and Syk are currently undergoing clinical trials for the treatment of diseases related to inflammation and autoimmunity.
Regulation (drugs tar) of Syk associated with autoimmune disease, inflammation and disease
1) Confidence 0.05 Published 2008 Journal Purinergic Signal Section Body Doc Link PMC2721774 Disease Relevance 0.98 Pain Relevance 0.22

General Comments

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